Прошу прощения за встревание, но ацетазоламид (диакарб) может быть использован для лечения водянки, согласно французскому опыту:
Rev Neurol (Paris). 1990;146(6-7):437-9.
[Acetazolamide: an alternative to shunting in normal pressure hydrocephalus? Preliminary results]
Aimard G, Vighetto A, Gabet JY, Bret P, Henry E.
Clinique Neurologique, Hopital Neurologique P. Wertheimer, Lyon.
From a series of 15 consecutive patients with a normal-pressure hydrocephalus examined over 2 years. 10 showed frank improvement with oral acetazolamide. The drug was a first-choice treatment in 5 cases and was given up after a spinal tap in 5 cases. Clinical response occurred even in the most severe cases, although it was slightly less impressive for intellectual impairment than for gait or bladder disturbances. Tolerance was excellent with a daily dose of 250 to 500 mg. The benefit remained stable on a more than 1 year follow-up in 8 cases. We suggest that acetazolamide should be tried in patients with normal pressure.
Кроме того этот препарат может применяться для определения показаний к шунтированию:
Acta Neurochir (Wien). 1999;141(11):1187-93.
Diamox((R)) challenge test to decide indications for cerebrospinal fluid shunting in normal pressure hydrocephalus.
Miyake H, Ohta T, Kajimoto Y, Deguchi J.
Department of Neurosurgery, Osaka Medical College, Japan.
OBJECTIVE: The indications for cerebrospinal fluid (CSF) shunting in patients with normal pressure hydrocephalus (NPH) have not been established. Establishment of clear-cut indications for this procedure is essential to ensure cost-effective, and safe treatment. We report the usefulness of the Diamox((R)) challenge test in evaluating indications for CSF shunting in patients with NPH. METHODS: Pre- and post-operative responses in cerebral blood flow (CBF) and intracranial pressure (ICP) to intravenous administration of Diamox((R)) 1000mg (Diamox((R)) administration) were analysed in 41 patients with NPH who were treated by ventriculoperitoneal (VP) shunt with a programmable valve and an on-off valve. RESULTS: The preoperative response of ICP to Diamox((R)) administration was more than 10 mmHg in most patients in whom the shunt was effective (shunt effective group), however, it was less than 10 mmHg in most patients in whom the shunt was ineffective (shunt non-effective group). Furthermore, the postoperative response of ICP to Diamox((R)) administration decreased to less than 10 mmHg in most patients in the shunt effective group. The increases in CBF in response to Diamox((R)) administration were similar in the two groups both before and after placement of the VP shunt. CONCLUSION: Patients in whom ICP increased by more than 10 mmHg in response to Diamox((R)) administration were regarded to have poor CSF circulation and to thus be candidates for CSF shunting. The Diamox((R)) challenge test is a simple, safe procedure, useful in evaluating the response to treatment.
Также он применяется для снижения внутричерепного давления.
Кстати, а Ваше внутричерепное давление каково? какие причины водянки: травма, кровоизлияние?