1. -, ,
    : 21
    : 31.05.2005, 19:29
  2. Ndima74 , ,
    : 26
    : 01.09.2004, 19:30
  3. : 1
    : 01.08.2004, 17:55
  4. : 2
    : 26.05.2004, 10:36
  5. : 1
    : 20.05.2004, 07:02

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    , , . Pubmed : Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products. .. , " " - . ( ): Clin Ter. 2004 Jul-Aug;155(7-8):347-51. Related Articles, Links





    [Diet and management of degenerative diseases of the retina (retinitis pigmentosa)]



    [Article in Italian]



    Miggiano GA, Falsini B.



    Centro di Ricerca in Nutrizione Umana, Istituto di Biochimica Clinica, Italia.



    Considerable progress has been made in the understanding and management of degenerative diseases of the retina. The dietetic intervention has been favourably proposed in the most common forms of retinitis pigmentosa, a condition potentially leading to blindness. Vitamin A has been shown to be effective in delaying progression of the disease. In these patients such treatment is the only possible therapy, to date, and a lifetime generous supplementation of retinol is advisable, together with a vitamin A-rich diet and/or a dietary supplement (e.g. carrot flour) or pharmacologic supplement of vitamin A. Supply of vitamin A in doses up to 25000 IU (7500 igr/day), even for several years, has so far proved safe from risk of occurrence of liver disease. A possible effect on hypercholesterolemia related to a very prolonged treatment in predisposed individuals can be avoided by using a special diet, particularly enriched with beta-carotene. Guidelines for preparing a diet, specially formulated to provide an elevated weekly supply of vitamin and/or its precursor (equal to 15000 IU or 5000 microg of RE, retinol equivalent) and to control possible risk factors related to dietetic manipulation (supply of fat lower than 30% of total calories, variable levels of cholesterol and polyunsaturated fatty acids n-3, n-6) are presented. As long as resolutive therapy is lacking, dietetic intervention plays a primary role, although underestimated, in the management of the patients suffering from retinitis pigmentosa. The diet is specifically characterized by presence of food with a high content of carotenoids, substances with a favourable and additive effect.



    PMID: 15553263 [PubMed - indexed for MEDLINE]

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