SHCHitovidka, hormones and preparations

[Vikta]

Hello.

32 years, the diagnosis - secondary sterility or barrenness. Three pregnancies, from them 2 - the mini-abortion, one (last) - stood. (5-6 weeks). Since August 2004 our attempts are unsuccessful. SG at the husband good.



Question the first.

One year ago (April 2004), after the stood pregnancy, surveyed a thyroid gland and have found 1,10,9 site.

Since February 2005 I accept l-thyroxine (75). For a year the site has not increased. Here data of the last uzi (June 2005):

Right: length 44, width 16, depth 16, volume 5,5, an isthmus 2,1

Left: length 44, width 15, depth 16, volume 5,4

Structure or Frame non-uniform, ehogennost normal, vascularization raised or increased, limf.uzly are not increased, okoloshchit.zhelezy not vizual.

The site of the left share: 10 h 12 h 7, contours equal, precise, obodok halo uniform, ehogennost izoehogennyj, structure or frame fibrous includings or incorporations, vascularization intraperinodul.

Have told or said, it is bad, that site.



December 2004: before treatment l-thyroxine

3 7,9 (4,1 - 9,2)

4 17 (10 - 23)

TTG 0,68 (0,23 - 3,4)

February 2005: Hormones on the basis of which has been appointed or nominated l-thyroxine (75)

4 10,88 (9 - 23,2)

TTG 1,53 (0,24 - 3,5)

mikros.a/O 0,5 (0 - 30)

June 2005: Hormones on a background of treatment (since March, 23rd 2005)

3 1,5 (1,0 - 2,8)

4 93 (53 - 158)

TTG 0,17 (0,23 - 3,4)

L-thyroxine I accept 75 since morning.

Since June the dose is changed by another vrachem: 50 since morning, 50 evening



Whether prompt, please, there is a necessity for a surgical intervention? Or in updating a dose. How in my case I need to concern to jodosoderzhashchim to products and medicines?



Question of the second.

Whether l-thyroxine reception influences rising of activation of thrombocytes?

Handed over a blood on a coagulogram + AFA. Are revealed AFA 8, 6 % (norm or rate up to 16, 4 %). Peresdala a -ferment method: 5,41 (N 0-10). Plus the raised or increased aggregation of thrombocytes. It is appointed or nominated Trombo Ass (1 in day). In a month has handed over AFA and parameters of intravascular activation of thrombocytes. AFA 11, 1 % (norm or rate up to 16, 4 %), t. e., the percent or interest has grown. Number of the thrombocytes involved in units 10, 7 (N 6, 1 7, 4). Curantylum (3 in tech is appointed or nominated. Day - 14 days). The diagnosis - hyperaggregation of thrombocytes.

After control AFA over a background of Curantylum I shall hand over gomotsistein and genetic markers of disturbance of coagulability of a blood (12 pieces).

Prompt, please, if AFA in norm or rate, medicines what for are appointed or nominated and the diagnosis is how much serious at planning pregnancy?



Question the third.

My Prolactinum 239 (67 - 726), is handed over on 5 d.m.ts. The endocrinologist has told or said, that I need to correct its or his level below 200 then I without problems shall become pregnant. Bromocriptinum is appointed or nominated. I accept analogue: bromergon 2,5 on 1/4 tablets in the evening the first 10 days, further on 1/2 tablets.

Prompt, whether so it? This preparation is how much harmful?



In advance I thank you for patience and the answer.

[Light]

Uvzhaemaja Vikta,

The convincing bases for purpose or appointment of a L-thyroxine and Bromocriptinum I do not see.

O.? site. More than 1 sm in diameter is a subject to a puncture biopsy.

In occasion of sterility or barrenness you at gynecologists were surveyed?

[Vikta]

Yes, I am surveyed. No obvious reasons of absence of pregnancy are present.

Hysteroscopy, GSG, a laparoscopy did not do or make.



Cycle regular 30-32 days. The ovulation on US occurs or happens at 15-16 d.ts. (one cycle completely traced by me on US).



On January, 29th 2005. I have come to the doctor with the diagnosis secondary sterility or barrenness (put in mine ZHK). Me have looked or seen on an armchair and have diagnosed: the Failure of function of ovaries of the implicit form, a dysmenorrhea.

Then have sent on analyses of hormones shchitovidki, on a sugar curve (5,2-5,6-5,9), and on 21-22 d.ts.: uzi, Progesteronum - 1,5 (ff 0,1-6; lf 10-89), Prolactinum 218,9 (67 - 720). US an ovulation has not shown, Progesteronum was practically on zero. BUT in this cycle I had a delay of 2 weeks. Has explained to me it is long maturing of a follicle. To retake Progesteronum has not appointed or nominated, has appointed or nominated again uzi on 21 (?) d.ts., has told or said to accept utrozhestan with 16 on 25 d.ts. Also has sent to the endocrinologist. The endocrinologist has registered l-thyroxine and has released or has let off good luck. US on 21 d.ts.na a background utrozhestana has not shown an ovulation (uzi did or made in the 12).

Then the doctor appoints or nominates to me stimulation of an ovulation klostibegitom!!! I esteemed the summary, of clause or article about klostile and was frightened. In fact she has not wanted to direct me with the husband neither on spermogrammu, nor on delivery of the same LG, FSG, etc., eventually, on GSG, on uzi in the middle of a cycle (12-13-14 d.ts.).

The diagnosis has been put on the basis of 2 US, one - in a cycle with 2 week delay, another - on a background of reception utrozhestana, plus low Progesteronum in a cycle with 2 week delay.

Further I was surveyed in the ZHK.

On April, 11-12th 2005 g (4-5 d.ts.)

LG 4,0 (1,1-8,7) ff

FSG 7,9 (1,8-11,3) ff

Testosteron-Depotum 1,3 (0,5-4,3)

DEA 9 (10-25)

4 2,1 (2-8)

Prolactinum 239 (67-726)

Oestradiolum 118 (100-600)

Hydrocortisone 382 (150-660)



On April, 29th 2005 (22 d.ts.)

Progesteronum 84,7 (10-89) on a background of reception utrozhestana vaginalno 1 2/



On May, 4th 2005

The blood on presence of specific antibodies is handed over: chlamydias, TSMV, toksoplazma, VPG, preearly fibers to VPG.

Are found out:

Chlamydias IgG 1 : 32

VPG I and II type IgG 1 : 100

IgG to preearly fibers VPG



The special attention has been directed on VPG, since after the stood pregnancy (in April 2004) by method PTSR has been revealed VPG II (toksoplazma, VPG I, TSMV, chlamydias, a ureaplasma, a mycoplasma hominus, a mycoplasma genit. - it is negative).



About AFA I wrote. Are revealed within the limits of norm or rate.



The prospective reason of absence of pregnancy: VPG + AFA.

[Light]

If last pregnancy has ended with a currettage, GSG it is represented expedient.

At normal permeability, presence of ovulations and good SG at the husband, - pregnancy will come or step without treatment.