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Просмотр полной версии : sulfazalazin



vivere
01.09.2004, 19:30
Hello! To me of 25 years, the diagnosis a pseudorheumatism. The doctor has appointed or nominated sulfazalazin (Salazopyrinum), I accept on 2 tablets 3 r. In day more than year.

Now the problem - the typed or collected 10 (!) kg of weight though I eat as always and now, despite of a diet to dump or reset them it does not turn out in any way. There can be it a preparation so has affected or influenced?

Tell or Say please, it is possible or probable? Or in vain I on tablets slander?

Thanks.

Yours faithfully, Elena

terra
01.09.2004, 19:30
In itself Sulfasalazinum should not lead to augmentation of mass of a body.

You do not accept more any preparations?

Zina Merz
01.09.2004, 19:30
In general, at least at animals, Sulfasalazinum broke processes of an absorption in an intestine:



Chadha S, Kanwar U, Sanyal SN.

Effect of sulfasalazine on adaptive and functional changes in intestine of normal and protein-calorie-malnourished rats.

Res Exp Med (Berl.) 1992; 192 (2):105-13.



On the other hand, some patients with RA and on SS all the same add in weight: so among 22 patients already at 15 was excess weight (BMI 30.6) and 5 have added on the average on 4,5 kg:



http: // ard.bmjjournals.com/cgi/content/full/61/1/66





If to go deep in teoretizirovanie the potential disturbances leading ekstravesu can be disturbance of a lipide and carbohydrate exchange at patients with RA when activity of disease is still high:



http: // www.pubmedcentral.nih.gov/articlerender.fcgi? tool=pubmed*amp; pubmedid=12453315



I do not know, whether will approve colleagues, but can it is meaningful check up a cholesterin and a level of a glucose? What seichas an ESR?

Leksus
01.09.2004, 19:30
Certainly! It is meaningful to learn or find out in general more detailed information on the patient with a pseudorheumatism.:)