Strong edemas of the left leg or foot

[Marina (Moscow)]

Hello the doctor! To me of 25 years. At me the left leg or foot recently swells, very strongly stop and a joint (right or does not swell at all, or an edema insignificant), the edema does not pass or take place neither since morning, nor by the evening. When he nevertheless falls down, on its or his place there are ecchymoses (last 1-2 months). On a femur and on an anticnemion appear, during an edema, deep "ruts". With what it is connected? It is necessary to hand over what analyses? And than it is possible to facilitate a status, diuretic already badly helps or assists.
Thanks for the answer.