Good afternoon. To my friend (78 years) have recommended to accept MEKSIDOL for...

[Mozhzhevelov S.B.]

Good afternoon. To my friend (78 years) have recommended to accept MEKSIDOL for normalization of a cerebral circulation. Whether there are no contraindications for reception, considering, what at it or her still DIABETUM and the HYPERTONIA? What dosage to her to apply?

[Chizhikov K.I.]

Meksidol, it is not a preparation improving a cerebral circulation, not a vascular preparation. At Diabetum and an idiopathic hypertensia if at her function of kidneys does not suffer, he is not counter-indicative and can be appointed or nominated.
I result or bring the detailed information on this preparation: 3 Oksi-6 metil-2 etilpiridinasuktsinat.
White or white with kremovatym a shade a crystalline powder. We shall easily dissolve in water.
On chemical structure or frame meksidol is corresponding or meeting emoksipinu salt of an amber acid (succinate).
Similarly to emoksipinu, meksidol is an inhibitor svobodnoradikalnyh processes (antioxidant), but renders more expressed antigipoksicheskoe action.
Meksidol possesses a wide spectrum of biological activity. He is effective at different kinds of a hypoxia: more expressed and long an effect, than Dibunolum (ionol) has. The preparation raises or increases fastness of an organism to kislorodzavisimym to pathological statuses (to a shock, disturbances of a cerebral circulation, etc.), improves mnesticheskie functions, reduces toxic effects of alcohol, etc.
Meksidol it is offered for treatment of acute disturbances of a cerebral circulation, distsirkuljatornoj to an encephalopathy, vegetososudistojdistonii, atherosclerotic disturbances of functions of a brain, for a cupping of an abstinent syndrome at an alcoholism and narcomanias, at other statuses, tissues accompanied by a hypoxia.
Apply meksidol intramusculary or intravenously (strujno or it is dropwise). Strujno the preparation is recommended to be entered for a cupping of an abstinent syndrome and vegetative and simpatoadrenalovyh paroxysms, and it is dropwise at acute disturbances of a cerebral circulation.
At intravenous introduction as a dissolvent it is recommended to use sterile water for injections. Strujno meksidol enter during 5 7 mines, it is dropwise - with rate of 60 drops in a minute. Doses appoint or nominate individually.
Begin treatment with a dose of 100 mg 1 3 times day, gradually raising or increasing a dose before reception of therapeutic effect. Duration of treatment and a choice of an individual dose depend on gravity of a status of the patient and efficiency of treatment. The maximal daily dose should not exceed 800 mg.
For treatment of acute disturbance cerebral circulations (insult) meksidol appoint or nominate intravenously dropwisely in a dose of 200 300 mg in the first 2 4 days, and then intramusculary on 100 mg 3 times a day.
Patients with dists irku ljatornoj an encephalopathy and a vegeto-vascular dystonia a preparation enter intramusculary in a dose of 50 100 mg 3 times into day.
At absginentnom a syndrome meksidol enter in a dose of 100 200 mg intramusculary 2 3 times into day or intravenously (driply) 1 2 times in day, and at neurotic and neurosolike frustration appoint or nominate intramusculary in a dose of 50 400 mg day.
To treatment of an atherosclerotic aphrenia at patients of advanced age meksidol apply intramusculary in a dose of 100 300 mg day.
At an acute antipsychotic intoxication the preparation is used intravenously strujno in a dose of 50 300 mg day.
Usually meksidol it is well transferred or carried. At some patients occurrence of a nausea and dryness in a mouth is possible or probable.
The preparation is counter-indicative at the expressed disturbances of functions of a liver and kidneys, at presence in the anamnesis of an allergy to a pyridoxine (vitamin 6).
The FORM of RELEASE: 5 % a solution in ampoules on 2 ml.
STORAGE: the List. In the place protected from light.