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MTL
15.06.2004, 11:21
Hello! Whether to all adult people having though any problems with health (especially if they are similar to descriptions on your site), it is necessary to pass or take place analyses on a mycoplasmosis and a clamidiosis? If yes, what method: immunoglobulins, PTSR (soskob, a blood)?

Dvorjanchikov Century
17.06.2004, 07:38
If the symptomatology unequivocally corresponds or meets described the diagnosis exposed on its or her basis, will be, on the average, more authentic, than exposed by results of the analysis. Effective (t. e. Calculated on all kinds and subspecies) popular methods of diagnostics of these infections all peerly does not exist. And even that are developed for separate, but by no means, not dominating kinds, have the lowest reliability - what there their developers approved or confirmed.

MTL
17.06.2004, 14:50
Thanks! And in your center what method of laboratory diagnostics of these infections use also what do not trust at all?

Dvorjanchikov Century
18.06.2004, 20:26
We apply a microscopy of the painted smears (MOM), the truth, fairly advanced. Earlier MOM was considered (however, and now still it is considered) referentnym a method. But when has begun orgy with a different sort immune, and further - and with genetic ways of diagnostics, MOM as the cheap competitor was oshelmovan and is named "insufficiently sensitive". Probably, he was not ideal, but had two conclusive advantages which are deprived modern methods: practically full absence "lozhnopolozhitelnosti" (the microbe is visible immediately in a microscope) and insusceptibility to every possible specific and immunologic differences patogenov. Differently, (within the limits of applicability) all is peer to method MOM, what infectious strain "to catch". The method direct the immunofluorescences (PIF), also considered referentnym (declared sensitivity of 65 %, lozhnopolozhitelnost - 2 3 %), is sensitive to nalichiju/to absence on membranes C. trachomatis their main membranous protein (MOMP), that shammy at which this protein is absent or something is blocked, meet all more often. Methods IFA and PTSR are not reliable and it is absolutely fair referentnymi at us do not admit (are supposed as auxiliary). For Chl. pneumoniae, Chl. psitacci and t. Item specific shirokodostupnyh diagnosticums also it is not developed not so (import and domestic "samopal" - it is not counted). In effect, these kinds now analytically do not come to light almost. From here enormous raskardash in estimations infitsirovannosti the population at different researchers - from 2 up to 80 %! And meanwhile, "unpretentious" MOM them quite reveals or taps. And okazvaetsja, that characteristic for these kinds diffusively located in a cytoplasma of epitheliocytes or epithelial cells reticular teltsa (RT) patogena meet many times more often, than "pasted" to a kernel or core of epitheliocyte or epithelial cell RT, characteristic for Chl. trachomatis! In essence, it means presence in a population of a uncontrollable pandemic. Business both with mycoplasmas, and with some other infections similarly is. We are compelled or forced to recognize brought from the analyses executed by a method the PIF and crop (if speech about mycoplasmas), however, almost always them we recheck. The same patients who has "good" analyses to treat sometimes easier, than to convince that to the illness they are obliged to infections.