What reasons of a macroamilasemia? For example, rising an amylase up to 2 comes to light or is taped...

[Martynova E.V.]

What reasons of a macroamilasemia? For example, rising an amylase up to 2010/ml due to a macroamylase comes to light or is taped. What additional inspection and treatment is necessary for the patient (onkopoisk it is spent in full)?

[Rasulov M.I.]

Onkopoisk spent in full means, that for exception periampuljarnoj or Virsungova a duct of a carcinoma you have spent including retrogradnuju holangiopankreatikografiju. And it has caused or called rising an amylase.

[Jerboa]

The macroamilasemia / MA/is the good-quality disease observable 1 of % in opr. Populations.
Linkage of a usual amylase of a blood with fibers / more often - antitelami/interferes with deducing or removing of this complex by kidneys. Not numerous cases of a combination MA with other diseases - SLE, UC, lymphoma, RA and other are known...

[Rasulov M.I.]

The amylase is presented by two isoenzymes: P-type, pancreatic (from a pancreas), S-type, salivary (from sialadens). Unlike the majority of enzymes, yo the-amylase is filtered in glomuluses of kidneys and contains in urine. There is also a macroamylase which is not allocated with kidneys iz-for the big sizes of a molecule, but can meet in Serum of a blood in norm or rate and at a pathology. Definition of a pancreatic isoenzyme has the greatest diagnostic importance.

In Serum of a blood at healthy people about 70 % of amylolytic activity it is necessary on salivary an isoenzyme, in urine approximately same percent or interest is necessary on pancreatic alfa-an amylase.

Activity of an amylase in Serum of a blood raises or increases at an acute pancreatitis (more, than in 5 times, basically, due to a pancreatic isoenzyme), at a cancer of a pancreas, a virus hepatitis, a lesion of sialadens (an epidemic parotitis), a renal failure, at reception of corticosteroid preparations, Salicylases, Tetracyclinum, Histaminum.

Activity of an amylase in Serum of a blood is lowered at the hepatitises, insufficient function of a pancreas, at a toxicosis of pregnancy.