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Просмотр полной версии : Indirect billirubin



Breeze
03.12.2003, 16:37
pozhajlusta explain as in an organism arises billirubin?
Whence undertakes direct and indirect?
How it is possible to adjust or regulate its or his level (indirect), any diet can eat?
Whether also it is possible velechit Syndrome ZHilbera?
Thanks.

gast
03.12.2003, 22:31
The bilirubin is formed in an organism as a result of an erythrocytolysis, mainly in a liver. (it is so-called free (he indirect) a bilirubin)
Formed as a result of disintegration of a hemoglobin
The free bilirubin in a blood incorporates or is bridged with
Albumin. In the subsequent there is a unit of a free (indirect) bilirubin from an albumin and its or his transformation into a glucuronide of a bilirubin.
Bond of a bilirubin with a glucuronic acid
Does or Makes its or his soluble in water, as provides
Its or His deducing or removing from an organism. Formed
The pigment a glucuronide-bilirubin is called connected
Or a direct bilirubin.
Syndrome (illness or disease) ZHilbera it is caused or called by genetically caused deficiency of enzyme gljukuroniltransferazy by means of which in hepatic cells from an indirect bilirubin it is formed by a straight line.

In connection with hereditary character of a pathology the probability of full treatment is small.
Rising of a level of a bilirubin at syndrome ZHilbera is provoked by appreciable physical and psychoemotional loads, alimentary errors, starvation, reception of some medicines, infectious diseases. Therefore the major importance in treatment has keeping a regimen (work, a delivery, rest), instead of reception of any medicines. Professional works are counter-indicative to patients sports. If the bilirubin nerezko is raised or increased (for example, in 2 times) necessity it or him "to lower" is not present. If rising of a bilirubin is more expressed and accompanied by delicacy and bad state of health, reception of special preparations is possible or probable

Breeze
04.12.2003, 12:27
Many thanks!!!!
It is difficultly treated when you do not understand as it occurs or happens:-)
There are some more questions:
In preparations which deduce or remove a bilirubin from a blood, sozherzhatsja enzyme gljukuroniltransferazy?
Whether this enzyme in any food stuffs contains?
Whether there are still similar preparations, except for izveztnyh to me (Corvalolum and Fenobarbitalum)?
The raised or increased level of a bilirubin can be connected with wrong functioning a thyroid gland?
Whether expediently to clean an intestine at the raised or increased bilirubin?
Whether the child can inherit this disease?

gast
04.12.2003, 14:06
No, gljukuroniltransferaza neither in food stuffs nor in preparations does not contain. Operating or working beginning is Fenobarbitalum (which also contains in Corvalolum and Valocordinum), he strengthens synthesis of enzyme in a liver.

Linkage and deducing or removing of a bilirubin from a blood plasma is meaningful only at very its or his greater or big value or meanings;importance and is carried out by a method of a plasmapheresis, introduction of an albumin, etc.
With a thyroid gland it is not connected in any way.
To clean an intestine unessentially.
As disease hereditary, can be passed by right of succession. If there is really confirmed syndrome ZHilbera, it is possible to consult with medical genetikom.

P.S.disease good-quality.

Breeze
04.12.2003, 14:41
54 indirect bilirubin (the general or common 58) it not an occasion to apply a method of a plasmapheresis?

I the first in family to that have diagnosed syndrome ZHilbera (in 22 years), before I have had been ill with an icterus in 6 years (has successfully recovered weeks for two) and plus mum who all life is excruciated by a liver and a cholic bubble (he at it or her any abnormal form).

Whether other diagnoses connected with the raised or increased level of a bilirubin are possible or probable?

Once again many thanks!;-)

gast
04.12.2003, 21:46
If are available in view of value or meaning;importance of a bilirubin in ???y/l, this average rising. Norm or rate of the general or common bilirubin - up to 20,5 ???y/l, indirect - up to 4,6.
At patients to an acute lesion of a liver happens - 400 and more.
With your parameters, especially if there are no signs, to spend a plasmapheresis it is not necessary.

Yes, there are also other illnesses or diseases with rising a level of an indirect bilirubin, for example, hemolitic anemias (destruction of erythrocytes-> accumulation of a bilirubin). The doctor also should distinguish one from another.

Ask, if that.;)

Breeze
05.12.2003, 08:10
Thanks:-)))))